苏高星

团队介绍

姓名：苏高星，

性别：男，

民族：汉，

出生年月：1986.07，

职称：副教授，

学历：博士研究生，

职务：无

研究方向：

基于纳米技术的疾病新型诊疗技术；

纳米生物传感分析；

纳米化员工物学

社会学术兼职：

Frontiers in Bioengineering and Biotechnology: Guest Associate Editor；

中国化学会会员；

多个SCI期刊的审稿人

基金项目：

1. 国家自然科学基金，面上项目，22076085，肠道内纳米颗粒生物分子冠的成分解析及在肠道吸收纳米颗粒中的作用研究，2021/01- 2024/12，63万，在研，主持

2. 国家自然科学基金，青年项目，21405084，蛋白质冠状物对纳米载体靶向功能的影响， 2015/01- 2017/12，25万，已结题，主持

3. 国家自然科学基金，重点项目，21137002，典型纳米材料的生物毒性效应及调控研究，2012/01-2016/12，308万，已结题，项目骨干

4. 国家自然科学基金，面上项目，81473089，大麻素CB1别构拮抗剂及其治疗尼古丁成瘾性作用研究，2015/01-2018/12，65万，已结题，项目骨干

5. 南通市科技计划项目，JC2020031，生物分子冠在肠道吸收口服纳米粒中的作用研究，2020/10- 2022/09，3万，在研，主持

6. 南通市科技计划项目，MS12015053，基于法尼基硫代水杨酸的混合胶束用于阿霉素的递送，2015/10-2018/09，3万，已结题，主持

7. 老员工创新训练计划项目，国家级，基于金纳米颗粒的生物传感器用于疾病标志物的检测，2014/05-2016/04，1.5万，已结题，指导教师

8. 老员工创新训练计划项目，省级，核壳结构金纳米棒-介孔硅纳米药物载体的制备及其用于肿瘤的化疗和热疗，2016/05-2017/04，0.5万，已结题，指导教师

科研成果：

以第一作者或通讯作者在Analytical Chemistry，Biosensors and Bioelectronics等国际权威期刊发表SCI收录论文22篇，影响因子大于10分有1篇，大于5分有14篇，所发表论文总被引用超1100次，H指数18。获授权国家发明专利3项。被评为江苏省高校“青蓝工程”优秀青年骨干教师，伟德BEVICTOR创新训练优秀指导老师。

代表性论文：

1. Wei S. Zhang^#, Jianbin Pan^#, Feng Li, Min Zhu, Mengting Xu, Hongyan Zhu, Yanyan Yu*, Gaoxing Su*. Reverse-Transcription Recombinase Polymerase Amplification Coupled CRISPR-Cas12a for Facile and Highly Sensitive Colorimetric SARS-CoV-2 Detection. Analytical Chemistry, 2021, 93(8), 4126-4133. (Front Cover Paper) (ESI高被引论文) （IF: 6.986）

2. Jiahui Wang, Gaoxing Su*, Xiliang Yan*, Wei Zhang, Jianbo Jia, Bing Yan*. Predicting cytotoxicity of binary pollutants towards a human cell panel in environmental water by experimentation and deep learning methods. Chemosphere, 2021, accepted. (IF: 7.086)

3. Xue Bai, Jiali Wang, Qingxin Mu*, Gaoxing Su*. In vivo protein corona formation: characterizations, effects on engineered nanoparticles’ biobehaviors, and applications. Frontiers in Bioengineering and Biotechnology, 2021, 9, 646708 (IF: 5.890)

4. Yanyan Yu^#, Wei S. Zhang^#, Yuehua Guo, Huaping Peng, Min Zhu, Dandan Miao, Gaoxing Su*. Engineering of exosome-triggered enzyme-powered DNA motors for highly sensitive fluorescence detection of tumor-derived exosomes. Biosensors & Bioelectronics, 2020, 167, 112482. (IF: 10.618)

5. Gaoxing Su^#, Min Zhu^#,Mengting Xu, Jianbin Pan, Yao Zhou, Hongyu Zhou, Wei S. Zhang, Yanli Tong*, Yanyan Yu*. Fluorescence resonance energy transfer-based DNA framework assembled split G-quadruplex nanodevices for microRNA sensing.Chemical Communications, 2020, 56(88), 13583-13586. (IF: 6.222)

6. Dandan Miao, Yanyan Yu*, Yong Chen, Yin Liu, Gaoxing Su*. Facile construction of i-motif DNA-conjugated gold nanostars as near-infrared and pH dual-responsive targeted drug delivery systems for combined cancer therapy. Molecular Pharmaceutics, 2020, 17(4), 1127-1138. (IF: 4.939)

7. Yanyan Yu, Yao Zhou, Min Zhu, Gaoxing Su*, Haohua Deng, Wei Chen*, Huaping Peng*. Dynamic split G-quadruplex programmed reversible nanodevice. Chemical Communications, 2019, 55(3), 389-392. (IF: 6.222)

8. Yanyan Yu, Yao Zhou, Min Zhu, Mingkai Liu, Hongyan Zhu, Yong Chen, Gaoxing Su*, Wei Chen*, Hua-Ping Peng*. Programming split G-quadruplex with DNA nanocage and microRNA imaging in live cells. Chemical Communications, 2019, 55(35), 5131-5134. (IF: 6.222)

9. Gaoxing Su, Dandan Miao, Yanyan Yu, Min Zhou, Peifu Jiao, Xiaolong Cao, Bing Yan*, Hongyan Zhu*. Mesoporous silica-coated gold nanostars with drug payload for combined chemo-photothermal cancer therapy. Journal of Drug Targeting, 2019, 27(2), 201-210. (IF: 5.121)

10. Yanyan Yu^#, Min Zhou^#, Wei Zhang, Lei Huang, Dandan Miao, Hongyan Zhu*, Gaoxing Su*. Rattle-type gold nanorods/porous-SiO₂ nanocomposites as near-infrared light activated drug delivery systems for cancer combined chemo-photothermal therapy. Molecular Pharmaceutics, 2019, 16(5), 1929-1938. (IF: 4.939)

11. Jinli Wang, Wei Zhang, Shuhuan Li, Dandan Miao, Guopei Qian, Gaoxing Su*. Engineering of Porous Silica Coated Gold Nanorods by Surface-protected Etching and Their Applications in Drug Loading and Combined Cancer Therapy. Langmuir, 2019, 35(44), 14238-14247. (IF: 3.882)

12. Gaoxing Su*, Huaqiao Jiang, Bohui Xu, Yanyan Yu, Xueqin Chen. Effects of Protein Corona on Active and Passive Targeting of Cyclic RGD Peptides Functionalized PEGylation Nanoparticles. Molecular Pharmaceutics, 2018, 15(11), 5019-5030. (IF: 4.939)

13. Gaoxing Su*, Huaqiao Jiang, Hongyan Zhu, Jing-Jing Lv, Guohai Yang, Bing Yan*, Jun-Jie Zhu*. Controlled Deposition of Palladium Nanodendrites on Tips of Gold Nanorods and Their Enhanced Catalytic Activity. Nanoscale, 2017, 9(34), 12494–12502. (IF: 7.790)

14. Gaoxing Su^#, Xiaofei Zhou^#, Hongyu Zhou*, Ye Li, Xianren Zhang, Yin Liu, Dapeng Cao, Bing Yan*. Size-Dependent Facilitation of Cancer Cell Targeting by Proteins Adsorbed on Nanoparticles.ACS Applied Materials & Interfaces, 2016, 8(44): 30037-30047. (IF: 9.229)